Research Associate/Senior Research Associate, Cell Engineering

Colossal Biosciences is hiring a Research Associate/Senior Research Associate in Cell Engineering in Dallas, TX. The role focuses on stem cell biology, including generation and editing of stem cells from non-model organisms. Responsibilities include deriving cell lines, optimizing gene editing, and collaborating with team members. Candidates should have experience in cell culture and molecular biology. This position offers competitive benefits and requires on-site work.
Colossal is looking for a talented research associate in stem cell biology with an interest in the generation, editing and differentiation of stem cells from non-model mammalian organisms. You will work closely with other lab team members in efforts to innovate on protocols of genome editing, reprogramming and lineage differentiation using cutting edge technologies.

This position is based on-site in Dallas, TX. Relocation assistance is available.

Duties and Responsibilities:
• Derive and characterize stable cell lines from primary tissues
• Test novel cell culture conditions and delivery methods to optimize gene editing
• Expand clonal cell lines for cryopreservation, genotyping and QC assays
• Develop cell assays to perform genotype to phenotype predictions
• Work with team members to integrate targeting, genotyping and QC workflows
• Schedule, analyze and execute experiments to deliver on project milestones
• Attend lab meetings, prepares reports and presentations on the progress of projects
• Demonstrate great organizational skills and excellent laboratory record maintenance

Required Skills and Abilities:
• Experience in primary cell line derivation, culture optimization and cryopreservation
• Experience with electroporation and transfection to maximize gene delivery and viability
• Experience immunostaining cells for flow cytometry and fluorescent microscopy
• Organized and comfortable multi-tasking to deliver on concurrent projects on time
• Strong written and oral communication skills, as well as creative problem-solving skills

Preferred Skills and Abilities:
• Experience with high throughput imaging platforms and data analysis
• Experience gene editing and expanding iPSCs for clonal cell line derivation
• Experience in molecular biology (DNA, RNA, protein extraction, qPCR etc)

Education and Experience:
• BA/BS/MA/MS in biological sciences, bioengineering, molecular biology, genetics, or any science related field.

What Colossal Offers You:
• Medical, dental, and vision coverage
• Unlimited PTO and company holidays so you can rest and recharge
• Flexible spending accounts (FSA)
• Company matched 401k retirement plan
• Paid parental leave up to 12 weeks
• Education reimbursement
• An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.

Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law

Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.

Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:
• #1 on the 50 Best Startups to Work For in Dallas in 2023!
• 100 Best Midsize Places to Work in Dallas in 2024 & 2025
• 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 & 2025
• 100 Best Midsize Places to Work in Boston in 2024 & 2025

Built In 2025 Award Lists

Great Place to Work Certification Page

Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.

Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!

Job posting details for Research Associate/Senior Research Associate, Cell Engineering at Colossal Biosciences in Dallas, TX. . ClimateTechList gathers 13,000+ job openings from over 778 climate tech companies and updates them daily.